Mid-gestational changes in cervicovaginal fluid cytokine levels in asymptomatic pregnant women are predictive markers of inflammation-associated spontaneous preterm birth
نویسندگان
چکیده
منابع مشابه
Biochemical Markers of Spontaneous Preterm Birth in Asymptomatic Women
Preterm birth is a delivery that occurs at less than 37 completed weeks of gestation and it is associated with perinatal morbidity and mortality. Spontaneous preterm birth accounts for up to 75% of all preterm births. A number of maternal or fetal characteristics have been associated with preterm birth, but the use of individual or group biochemical markers have advanced some of the understandi...
متن کاملCervicovaginal Fluid Acetate: A Metabolite Marker of Preterm Birth in Symptomatic Pregnant Women
Changes in vaginal microbiota that is associated with preterm birth (PTB) leave specific metabolite fingerprints that can be detected in the cervicovaginal fluid (CVF) using metabolomics techniques. In this study, we characterize and validate the CVF metabolite profile of pregnant women presenting with symptoms of threatened preterm labor (PTL) by both 1H-nuclear magnetic resonance spectroscopy...
متن کاملرابطه زایمان زودرس با β-H.C.G ترشحات سرویکوواژینال
Background and purpose: New biochemical markers(Fibronection, esteriol, à- feto protein,…) to predict spontaneous preterm birth give a more precise and earlier diagnosis than the usual ones( previous history, risk scoring system,…) there are many women with no obvois risk factors who deliver prematurely. The main purpose of this study was to determine the relationship between preterm delivery...
متن کاملInflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women
RESEARCH QUESTION Preterm birth (PTB) is the leading cause of perinatal mortality worldwide, with the greatest burden occurring in resource-constrained settings. Based on the hypothesis that altered placental angiogenesis and inflammation early in pregnancy lead to PTB, we examined whether levels of inflammatory and angiogenic mediators, measured early in pregnancy, were predictive of spontaneo...
متن کاملMetabolite Profile of Cervicovaginal Fluids from Early Pregnancy Is Not Predictive of Spontaneous Preterm Birth.
In our study, we used a mass spectrometry-based metabolomic approach to search for biomarkers that may act as early indicators of spontaneous preterm birth (sPTB). Samples were selected as a nested case-control study from the Screening for Pregnancy Endpoints (SCOPE) biobank in Auckland, New Zealand. Cervicovaginal swabs were collected at 20 weeks from women who were originally assessed as bein...
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ژورنال
عنوان ژورنال: Journal of Reproductive Immunology
سال: 2018
ISSN: 0165-0378
DOI: 10.1016/j.jri.2018.01.001